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R. LUCHETTI1,2, S. TOGNON3, M. CACCIAVILLANI4, S. RONCO5, N. BUZZELLI6, G. LANNI7.

Abstract

OBJECTIVE: To evaluate the current management of carpal tunnel syndrome (CTS) at a national level.
PATIENTS AND METHODS: A multicentric ob- servational study was conducted in 34 Italian cen- ters by specialists participating in the Manage- ment of Peripheral Neuropathies Study Group on 377 patients (age, mean±SD 56±14.4 years, 73.2% females) with CTS. The characteristics of the disease and its management were recorded at baseline and during a 2-month follow-up using a standardized clinical record and assessed with validated clinical tests.
RESULTS: A wide variability in the interven- tions prescribed and classi ed according to three categories (physical, pharmacological and neurotrophic therapies) was evident. A sub- group of 303 patients was treated with a com- bination of neurotrophic agents containing al- pha-lipoic acid (ALA). At the end of the follow-up, a general improvement in symptoms and func- tional impairment was observed, with a signi – cant reduction in BCTQ (Boston Carpal Tunnel Questionnaire) (p<0.001) and in NRS (Pain Nu- meric Rating Scale, p<0.001 for both nocturnal and diurnal pain).
CONCLUSIONS: An appropriate approach to CTS implies a multimodal and multidisciplinary management, involving several specialists and using a variety of conservative interventions. Conservative (physical and pharmacological) in- terventions can provide a clinical improvement in patients with CTS.